FUROSEMIDE (LASIX)

Class
Description
Onset and Duration
Indications
Contraindications
Adverse Reactions
Drug Interactions
How Supplied
Dosage and Administration
Special Considerations

FUROSEMIDE (LASIX)
Class

Diuretic

FUROSEMIDE (LASIX)
Description

Furosemide is a potent diuretic that inhibits the reabsorption of sodium and chloride in the proximal tubule and loop of Henle.

FUROSEMIDE (LASIX)
Onset & Duration

Onset:

(PO) 30-60 min (IV) Within 15-20 min

Duration:

4-6 hr

FUROSEMIDE (LASIX)
Indications

Pulmonary edema
Congestive heart failure

FUROSEMIDE (LASIX)
Contraindications

Anuria
Hypersensitivity
States of severe electrolyte depletion

FUROSEMIDE (LASIX)
Adverse Reactions

Hypotension
ECG changes
Chest pain
Dry mouth
Hypochloremia
Hypokalemia
Hyponatremia
Hyperglycemia

FUROSEMIDE (LASIX)
Drug Interactions

Digitalis toxicity may be potentiated by the potassium depletion that can result from furosemide administration.
Lithium toxicihy may be potentiated by sodium depletion.
Compatible with D5W, NS, LR solutions.

FUROSEMIDE (LASIX)
How Supplied

Tablet:

20, 40, 80 mg

Parenteral:

10 mg/ml in 2-ml ampule, 100 mg/ml in 10-ml vial

FUROSEMIDE (LASIX)
Dosage and Administration

Adult:

0.5-1.0 mg/kg IV injected slowly

Pediatric:

1 mg/kg/dose q 12 hr

FUROSEMIDE (LASIX)
Special Considerations

Pregnancy safety: Category C.
Furosemide has been known to cause fetal abnormalities.
Should be protected from light.